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KMID : 0360220170580020222
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Journal of the Korean Ophthalmological Society
2017 Volume.58 No. 2 p.222 ~ p.225
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Solitary Neurofibroma Occurred on the Eyelid Margin without Neurofibromatosis: A Case Report
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Kang Yeon-Soo
Choi Won
Kim Ga-Eon
Yoon Kyung-Chul
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Abstract
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Purpose: We report a rare case of solitary neurofibroma on the eyelid margin without neurofibromatosis.
Case summary: A 46-year-old male presented with a well-define small nodular lesion on the right upper eyelid margin that had not changed for 10 years. Surgical excision and biopsy were performed. Histological examination showed spindle-shaped cells in the fibrous stroma on hematoxylin & eosin staining, and immunohistochemical staining revealed S-100 protein-positive cells. Dermatologic, neurologic, and genetic evaluations showed no evidence of systemic neurofibromatosis. Six months after operation, there was no evidence of local recurrence.
Conclusions: To the best of our knowledge, this is the first case of solitary neurofibroma involving the eyelid margin without neurofibromatosis in Korea. Neurofibroma should be considered in a differential diagnosis of eyelid mass and can be successfully managed with surgical excision.
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KEYWORD
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Eyelid mass, Neurofibroma, Neurofibromatosis
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